• Immunohistochemical analysis of paraffin-embedded Human stomach. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
  • Immunohistochemical analysis of paraffin-embedded Human stomach. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
  • Immunohistochemical analysis of paraffin-embedded Human stomach. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).
  • Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using CD 15 Mouse mAb diluted at 1:500.
  • Immunofluorescence analysis of Human-liver-cancer tissue. 1, CD15 monoclonal antibody (Q89) (red) was diluted at 1:200 (4°C, overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).3, Picture B: DAPI (blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B
  • Immunohistochemical analysis of paraffin-embedded Human-lung-cancer tissue. 1, CD15 monoclonal antibody (Q89) was diluted at 1:200 (4°C, overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval (>98°C, 20min). 3, Secondary antibody was diluted at 1:200 (room tempeRature, 30min). Negative control was used by secondary antibody only.

Anti-FUT4 antibody [Q89] (STJ97007)

SKU:
STJ97007

£46.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Alpha-1, 3-fucosyltransferase 4 is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: Q89
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC 1:200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FUT4
Gene ID: 2526
Uniprot ID: FUT4_HUMAN
Specificity: The antibody detects endogenous CD15 protein.
Immunogen: Synthetic Peptide of CD15
Function Isoform Short: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis. In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Isoform Long: Does not generate Lewis X antigens.
Protein Name Alpha-(1 -3-Fucosyltransferase 4
4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase
Elam-1 Ligand Fucosyltransferase
Fucosyltransferase 4
Fucosyltransferase Iv
Fuc-Tiv
Fuct-Iv
Galactoside 3-L-Fucosyltransferase
Database Links Reactome: R-HSA-9037629
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Membrane-Bound Form In Trans Cisternae Of Golgi
Alternative Antibody Names Anti-Alpha-(1 -3-Fucosyltransferase 4 antibody
Anti-4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase antibody
Anti-Elam-1 Ligand Fucosyltransferase antibody
Anti-Fucosyltransferase 4 antibody
Anti-Fucosyltransferase Iv antibody
Anti-Fuc-Tiv antibody
Anti-Fuct-Iv antibody
Anti-Galactoside 3-L-Fucosyltransferase antibody
Anti-FUT4 antibody
Anti-ELFT antibody
Anti-FCT3A antibody

Information sourced from Uniprot.org

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