• Immunohistochemistry analysis of FucT-IV antibody in paraffin-embedded human breast carcinoma tissue.

Anti-FUT4 antibody (22-71 aa) (STJ92091)

SKU:
STJ92091

Current Stock:
Host: Rabbit
Applications: IHC/IF/IHC/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Alpha-1, 3-fucosyltransferase 4 (22-71 aa) is suitable for use in Immunohistochemistry, Immunofluorescence, Immunohistochemistry and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FUT4
Gene ID: 2526
Uniprot ID: FUT4_HUMAN
Immunogen Region: 22-71 aa
Specificity: CD15 Polyclonal Antibody detects endogenous levels of CD15 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human FucT-IV at the amino acid range 22-71
Function Isoform Short: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis. In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Isoform Long: Does not generate Lewis X antigens.
Protein Name Alpha-(1 -3-Fucosyltransferase 4
4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase
Elam-1 Ligand Fucosyltransferase
Fucosyltransferase 4
Fucosyltransferase Iv
Fuc-Tiv
Fuct-Iv
Galactoside 3-L-Fucosyltransferase
Database Links Reactome: R-HSA-9037629
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Membrane-Bound Form In Trans Cisternae Of Golgi
Alternative Antibody Names Anti-Alpha-(1 -3-Fucosyltransferase 4 antibody
Anti-4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase antibody
Anti-Elam-1 Ligand Fucosyltransferase antibody
Anti-Fucosyltransferase 4 antibody
Anti-Fucosyltransferase Iv antibody
Anti-Fuc-Tiv antibody
Anti-Fuct-Iv antibody
Anti-Galactoside 3-L-Fucosyltransferase antibody
Anti-FUT4 antibody
Anti-ELFT antibody
Anti-FCT3A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance