• STJ71797 (1µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.
  • STJ71797 (2µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Anti-FTH1 antibody (C-Term) (STJ71797)

SKU:
STJ71797-100

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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-FTH1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:2000.
WB: Approx 20kDa band observed in Human Placenta lysates (calculated MW of 21.2kDa according to NP_002023.2). Recommended concentration: 0.3-1µg/ml. Primary incubation was 1 hour.
IHC:
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: FTH1
Gene ID: 2495
Uniprot ID: FRIH_HUMAN
Immunogen Region: C-Term
Accession Number: NP_002023.2
Immunogen Sequence: DKHTLGDSDNES
Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron.
Protein Name Ferritin Heavy Chain
Ferritin H Subunit
Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed
Database Links Reactome: R-HSA-3000480
Reactome: R-HSA-432722
Reactome: R-HSA-6798695
Reactome: R-HSA-917937
Cellular Localisation Cytoplasm
Lysosome
Cytoplasmic Vesicle
Autophagosome
Alternative Antibody Names Anti-Ferritin Heavy Chain antibody
Anti-Ferritin H Subunit antibody
Anti-Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed antibody
Anti-FTH1 antibody
Anti-FTH antibody
Anti-FTHL6 antibody
Anti-OK antibody
Anti-SW-cl.84 antibody
Anti-PIG15 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance