Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-FSTL1 (1-308) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FSTL1 |
Gene ID: |
11167 |
Uniprot ID: |
FSTL1_HUMAN |
Immunogen Region: |
1-308 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-308 of human FSTL1 (NP_009016.1). |
Immunogen Sequence: |
MWKRWLALALALVAVAWVRA EEELRSKSKICANVFCGAGR ECAVTEKGEPTCLCIEQCKP HKRPVCGSNGKTYLNHCELH RDACLTGSKIQVDYDGHCKE KKSVSPSASPVVCYQSNRDE LRRRIIQWLEAEIIPDGWFS KGSNYSEILDKYFKNFDNGD SRLDSSEFLKFVEQNETAIN ITTYPDQENNKLLRGLCVDA LIELSDENADWKLSFQEFLK CLNPSFNPPEKKCALEDET |
Tissue Specificity | Overexpressed in synovial tissues from rheumatoid arthritis. |
Function | Secreted glycoprotein that is involved in various physiological processes, such as angiogenesis, regulation of the immune response, cell proliferation and differentiation. Plays a role in the development of the central nervous system, skeletal system, lungs, and ureter. Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes. Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors. |
Protein Name | Follistatin-Related Protein 1Follistatin-Like Protein 1 |
Database Links | Reactome: R-HSA-201451Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Follistatin-Related Protein 1 antibodyAnti-Follistatin-Like Protein 1 antibodyAnti-FSTL1 antibodyAnti-FRP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance