| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FSHR (631-695) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FSHR |
| Gene ID: |
2492 |
| Uniprot ID: |
FSHR_HUMAN |
| Immunogen Region: |
631-695 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 631-695 of human FSHR (NP_000136.2). |
| Immunogen Sequence: |
KNFRRDFFILLSKCGCYEMQ AQIYRTETSSTVHNTHPRNG HCSSAPRVTSGSTYILVPLS HLAQN |
| Tissue Specificity | Sertoli cells and ovarian granulosa cells. |
| Post Translational Modifications | Sulfated. N-glycosylated.indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone. |
| Function | G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. |
| Protein Name | Follicle-Stimulating Hormone ReceptorFsh-RFollitropin Receptor |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Follicle-Stimulating Hormone Receptor antibodyAnti-Fsh-R antibodyAnti-Follitropin Receptor antibodyAnti-FSHR antibodyAnti-LGR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
