| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FERM and PDZ domain-containing protein 2 (1161-1211 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FRMPD2 |
| Gene ID: |
143162 |
| Uniprot ID: |
FRPD2_HUMAN |
| Immunogen Region: |
1161-1211 aa |
| Specificity: |
This antibody detects endogenous levels of FRPD2 at Human |
| Immunogen: |
Synthesized peptide derived from the human FRPD2 at the amino acid range 1161-1211 |
| Function | Functions as a scaffold protein and likely plays a role in N-methyl-D-aspartic acid receptor (NMDAR)-mediated synaptic excitatory transmission. May be involved in synapse formation in cone photoreceptor cells. May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). May play a role in the regulation of NOD2-mediated NF-kappa-B activation in immune response. |
| Protein Name | Ferm And Pdz Domain-Containing Protein 2Pdz Domain-Containing Protein 4Pdz Domain-Containing Protein 5c |
| Cellular Localisation | CytoplasmBasolateral Cell MembraneCell JunctionTight JunctionPostsynaptic DensityColocalizes With Ctnnb1Cdh1 And Pkp4 At The Basolateral MembraneColocalizes With Tjp1 At Tight JunctionsIts Recruitment To Cell-Cell Contacts Requires Cdh1Colocalizes With Nod2 To The Basolacteral Membrane In Intestinal Epithelial Cells |
| Alternative Antibody Names | Anti-Ferm And Pdz Domain-Containing Protein 2 antibodyAnti-Pdz Domain-Containing Protein 4 antibodyAnti-Pdz Domain-Containing Protein 5c antibodyAnti-FRMPD2 antibodyAnti-PDZD5C antibodyAnti-PDZK4 antibodyAnti-PDZK5C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
