| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FREM2 |
| Gene ID: | 341640 |
| Uniprot ID: | FREM2_HUMAN |
| Immunogen Region: | 47-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 47-300 of human FREM2 (NP_997244.4). |
| Immunogen Sequence: | QPAAFGRALLSPGLAGAAGV PAEEAIVLANRGLRVPFGRE VWLDPLHDLVLQVQPGDRCA VSVLDNDALAQRPGRLSPKR FPCDFGPGEVRYSHLGARSP SRDRVRLQLRYDAPGGAVVL PLVLEVEVVFTQLEVVTRNL PLVVEELLGTSNALDARSLE FAFQPETEECRVGILSGLGA LPRYGELLHYPQVPGGAREG GAPETLLMDCKAFQELGVRY RHTAASRSPNRDWIPMVVE |
| Function | Extracellular matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia. Required for epidermal adhesion. Involved in the development of eyelids and the anterior segment of the eyeballs. |
| Protein Name | Fras1-Related Extracellular Matrix Protein 2Ecm3 Homolog |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Fras1-Related Extracellular Matrix Protein 2 antibodyAnti-Ecm3 Homolog antibodyAnti-FREM2 antibody |
Information sourced from Uniprot.org