Name: Anti-FPR1 antibody (155-204 aa) (STJ93133)
SKU: STJ93133
Availability: InStock

Anti-FPR1 antibody (155-204 aa) (STJ93133)

SKU:

STJ93133

£49.00 - £261.00

Short Description :	Rabbit polyclonal anti-fMet-Leu-Phe receptor (155-204 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:	WB/IHC/IF/ELISA
Host:	Rabbit
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Isotype:	IgG
Conjugation:	Unconjugated
Concentration:	1 mg/mL
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FPR1
Gene ID:	2357
Uniprot ID:	FPR1_HUMAN
Immunogen:	The antiserum was produced against synthesized peptide derived from the human FPR1 at the amino acid range 155-204
Immunogen Region:	155-204 aa
Specificity:	FPR1 Polyclonal Antibody detects endogenous levels of FPR1 protein.

Post Translational Modifications	Phosphorylated.which is necessary for desensitization.
Function	High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis.
Protein Name	Fmet-Leu-Phe Receptor Fmlp Receptor N-Formyl Peptide Receptor Fpr N-Formylpeptide Chemoattractant Receptor
Database Links	Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6783783 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Internalizes In Presence Of Its Ligands Fmlp Tafa4 And Ctsg
Alternative Antibody Names	Anti-Fmet-Leu-Phe Receptor antibody Anti-Fmlp Receptor antibody Anti-N-Formyl Peptide Receptor antibody Anti-Fpr antibody Anti-N-Formylpeptide Chemoattractant Receptor antibody Anti-FPR1 antibody

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJ93319	Anti-GPR108 antibody (155-204 aa) (STJ93319)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/IF/ELISA
STJ95427	Anti-RFPL4A antibody (155-204 aa) (STJ95427)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/ELISA/IHC
STJ95795	Anti-SSTR4 antibody (155-204 aa) (STJ95795)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/ELISA
STJ95441	Anti-RGS7 antibody (155-204 aa) (STJ95441)	Rabbit	Polyclonal	Human/Mouse/Rat	WB/ELISA/IHC
STJ90488	Anti-Phospho-STK11-Thr189 antibody (155-204 aa) (STJ90488)	Rabbit	Polyclonal	Human/Mouse	WB/ELISA

Anti-FPR1 antibody (155-204 aa) (STJ93133)

General Information