Anti-FOXP2 antibody (Internal) (STJ71049)

SKU:
STJ71049-100
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Short Description :Goat polyclonal antibody anti-FOXP2 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications.
Applications:Pep-ELISA/IHC
Host:Goat
Reactivity:Human/Mouse/Rat/Cat/Dog/Pig/Cow/Zebrafish
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.5 mg/mL
Purification:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Dilution Range:Peptide ELISA: antibody detection limit dilution 1:64000.
WB: Preliminary testing showed an approx 90kDa band in Human Cerebellum lysate and an approx 75kDa band in Rat Brain lysate after 0.3ug/ml staining. An additional band of unknown identity
Formulation:0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Storage Instruction:Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol:FOXP2
Gene ID:93986
Uniprot ID:FOXP2_HUMAN
Accession Number:NP_055306.1; NP_683696.2; NP_683697.2; NP_683698.2; NP_001166237.1
Immunogen Region:Internal
Immunogen Sequence:DEVEYQKRRSQKIT
Specificity:This antibody is expected to recognize isoform I (NP_055306.1) , isoform II (NP_683696.2) , isoform IV (NP_683698.2) and isoform V (NP_001166237.1).
Function Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
Protein Name Forkhead Box Protein P2
Cag Repeat Protein 44
Trinucleotide Repeat-Containing Gene 10 Protein
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Forkhead Box Protein P2 antibody
Anti-Cag Repeat Protein 44 antibody
Anti-Trinucleotide Repeat-Containing Gene 10 Protein antibody
Anti-FOXP2 antibody
Anti-CAGH44 antibody
Anti-TNRC10 antibody

Information sourced from Uniprot.org