| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Mouse/Rat/Cat/Dog/Pig/Cow/Zebrafish |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-FOXP2 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary testing showed an approx 90kDa band in Human Cerebellum lysate and an approx 75kDa band in Rat Brain lysate after 0.3ug/ml staining. An additional band of unknown identity |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | FOXP2 |
| Gene ID: | 93986 |
| Uniprot ID: | FOXP2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_055306.1; NP_683696.2; NP_683697.2; NP_683698.2; NP_001166237.1 |
| Specificity: | This antibody is expected to recognize isoform I (NP_055306.1) , isoform II (NP_683696.2) , isoform IV (NP_683698.2) and isoform V (NP_001166237.1). |
| Immunogen Sequence: | DEVEYQKRRSQKIT |
| Function | Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language. |
| Protein Name | Forkhead Box Protein P2Cag Repeat Protein 44Trinucleotide Repeat-Containing Gene 10 Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein P2 antibodyAnti-Cag Repeat Protein 44 antibodyAnti-Trinucleotide Repeat-Containing Gene 10 Protein antibodyAnti-FOXP2 antibodyAnti-CAGH44 antibodyAnti-TNRC10 antibody |
Information sourced from Uniprot.org