Western blot analysis of lysates from HeLa cells, using FOXD3 Rabbit polyclonal antibody (STJ23694). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-FOXD3 antibody (322-335) (STJ23694)

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STJ23694
£112.50 - £524.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FOXD3
Gene ID: 27022
Uniprot ID: FOXD3_HUMAN
Immunogen Region: 322-335
Specificity: A synthetic peptide corresponding to a sequence within amino acids 322-335AA of human FOXD3.
Tissue Specificity Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.
Function Binds to the consensus sequence 5'-AATTAGTTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Negatively regulates transcription of transcriptional repressor RHIT/ZNF205. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
Protein Name Forkhead Box Protein D3
Hnf3/Fh Transcription Factor Genesis
Database Links Reactome: R-HSA-2892247
Reactome: R-HSA-9856649
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Forkhead Box Protein D3 antibody
Anti-Hnf3/Fh Transcription Factor Genesis antibody
Anti-FOXD3 antibody
Anti-HFH2 antibody

Information sourced from Uniprot.org

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