Anti-FOXD3 antibody (211-260 aa) (STJ93108)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human FOXD3 at the amino acid range 211-260
General Information
| Short Description | Rabbit polyclonal anti-Forkhead box protein D3 (211-260 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FOXD3 |
| Gene ID | 27022 |
| Uniprot ID | FOXD3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human FOXD3 at the amino acid range 211-260 |
| Immunogen Region | 211-260 aa |
| Specificity | FoxD3 Polyclonal Antibody detects endogenous levels of FoxD3 protein. |
Additional Info
| Function | Binds to the consensus sequence 5'-AATTAGTTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Negatively regulates transcription of transcriptional repressor RHIT/ZNF205. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. |
| Protein Name | Forkhead Box Protein D3Hnf3/Fh Transcription Factor Genesis |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-9856649 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein D3 antibodyAnti-Hnf3/Fh Transcription Factor Genesis antibodyAnti-FOXD3 antibodyAnti-HFH2 antibody |
Information sourced from Uniprot.org