Anti-FOLR2/FR-Beta antibody [SAA1933] (STJA0020361)

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STJA0020361
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Short Description :Mouse monoclonal Folate Receptor Beta antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Clonality :Monoclonal
Clone ID :SAA1933
Isotype:IgG2a
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Protein A/G purified from cell culture supernatant
Formulation:0.01M PBS, pH 7.4.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol:FOLR2
Gene ID:2350
Uniprot ID:FOLR2_HUMAN
Post Translational Modifications N-glycosylated.
Function Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Protein Name Folate Receptor Beta
Fr-Beta
Folate Receptor 2
Folate Receptor - Fetal/Placental
Placental Folate-Binding Protein
Fbp
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-196757
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Antibody Names Anti-Folate Receptor Beta antibody
Anti-Fr-Beta antibody
Anti-Folate Receptor 2 antibody
Anti-Folate Receptor - Fetal/Placental antibody
Anti-Placental Folate-Binding Protein antibody
Anti-Fbp antibody
Anti-FOLR2 antibody

Information sourced from Uniprot.org

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