Anti-FOLR2 antibody [EM-35] (STJ16103138)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenBW5147alpha, beta-cells
General Information
| Short Description | Mouse monoclonal anti-FOLR2 for use in FC, IP, WB and ICC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IP/WB/ICC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | EM-35 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by protein-A affinity chromatography. |
| Formulation | Phosphate buffered saline (PBS) , pH 7.4, 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | FOLR2 |
| Gene ID | 2350 |
| Uniprot ID | FOLR2_HUMAN |
| Immunogen | BW5147alpha, beta-cells |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
| Protein Name | Folate Receptor BetaFr-BetaFolate Receptor 2Folate Receptor - Fetal/PlacentalPlacental Folate-Binding ProteinFbp |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196757 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
| Alternative Antibody Names | Anti-Folate Receptor Beta antibodyAnti-Fr-Beta antibodyAnti-Folate Receptor 2 antibodyAnti-Folate Receptor - Fetal/Placental antibodyAnti-Placental Folate-Binding Protein antibodyAnti-Fbp antibodyAnti-FOLR2 antibody |
Information sourced from Uniprot.org