Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FNTA |
Gene ID: |
2339 |
Uniprot ID: |
FNTA_HUMAN |
Specificity: |
This antibody detects endogenous levels of FNTA at Human, Mouse, Rat |
Immunogen: |
Synthesized peptide derived from human FNTA |
Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. |
Protein Name | Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit AlphaCaax Farnesyltransferase Subunit AlphaFtase-AlphaRas Proteins Prenyltransferase Subunit AlphaType I Protein Geranyl-Geranyltransferase Subunit AlphaGgtase-I-Alpha |
Database Links | Reactome: R-HSA-111465Reactome: R-HSA-2514859Reactome: R-HSA-9648002Reactome: R-HSA-9679191 |
Alternative Antibody Names | Anti-Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha antibodyAnti-Caax Farnesyltransferase Subunit Alpha antibodyAnti-Ftase-Alpha antibodyAnti-Ras Proteins Prenyltransferase Subunit Alpha antibodyAnti-Type I Protein Geranyl-Geranyltransferase Subunit Alpha antibodyAnti-Ggtase-I-Alpha antibodyAnti-FNTA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance