Anti-FLII antibody (STJA0009746)

SKU:
STJA0009746
£48.00 - £252.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Protein flightless-1 homolog is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FLII
Gene ID: 2314
Uniprot ID: FLII_HUMAN
Specificity: This antibody detects endogenous levels of FLII at Human, Mouse
Immunogen: Synthesized peptide derived from human FLII
Function Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling.
Protein Name Protein Flightless-1 Homolog
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cell Projection
Podosome
Cell Junction
Focal Adhesion
Colocalizes To Actin-Rich Structures In Blastocysts And
Together With Hras
Rhoa And Cdc42
In Migrating Fibroblasts
Localizes To Centrosomes
Localized To The Core Of Macrophage Podosomes
Alternative Antibody Names Anti-Protein Flightless-1 Homolog antibody
Anti-FLII antibody
Anti-FLIL antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ117468 Anti-FLII antibody (400-660) (STJ117468) Rabbit Polyclonal Human/Mouse/Rat WB/IHC-P/ELISA
STJE0008940 Human FLII (Flightless I Homolog) Sandwich ELISA Kit Kit (STJE0008940) Human ELISA
STJE0015319 Human FLII (Flightless I Homolog) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015319) Human ELISA
STJ90000 Anti-ACR antibody (40-120 aa) (STJ90000) Rabbit Polyclonal Human/Rat/Mouse WB/IHC/IF/ELISA
STJE0010429 Human LRRFIP1 (Leucine Rich Repeat In FLII Interacting Protein 1) Sandwich ELISA Kit Kit (STJE0010429) Human ELISA
!