Western blot analysis of extracts of various cell lines, using FKBP1B antibody (STJ111554) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-FKBP1B antibody (1-80) (STJ111554)

SKU:
STJ111554
£112.50 - £524.50
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:20-1:50
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FKBP1B
Gene ID: 2281
Uniprot ID: FKB1B_HUMAN
Immunogen Region: 1-80
Specificity: A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1).
Immunogen Sequence: MGVEIETISPGDGRTFPKKG QTCVVHYTGMLQNGKKFDSS RDRNKPFKFRIGKQEVIKGF EEGAAQLGPLSPLPICPHPC
Tissue Specificity Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
Function Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Protein Name Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1b
Ppiase Fkbp1b
12.6 Kda Fk506-Binding Protein
12.6 Kda Fkbp
Fkbp-12.6
Fk506-Binding Protein 1b
Fkbp-1b
Immunophilin Fkbp12.6
Rotamase
H-Fkbp-12
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-5578775
Cellular Localisation Cytoplasm
Sarcoplasmic Reticulum
Alternative Antibody Names Anti-Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1b antibody
Anti-Ppiase Fkbp1b antibody
Anti-12.6 Kda Fk506-Binding Protein antibody
Anti-12.6 Kda Fkbp antibody
Anti-Fkbp-12.6 antibody
Anti-Fk506-Binding Protein 1b antibody
Anti-Fkbp-1b antibody
Anti-Immunophilin Fkbp12.6 antibody
Anti-Rotamase antibody
Anti-H-Fkbp-12 antibody
Anti-FKBP1B antibody
Anti-FKBP12.6 antibody
Anti-FKBP1L antibody
Anti-FKBP9 antibody
Anti-OTK4 antibody

Information sourced from Uniprot.org

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