Anti-Fibrillin 2 antibody (Internal) (STJ70818)

SKU:
STJ70818-100
€241.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Goat
Applications: Pep-ELISA
Reactivity: Human/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-Fibrillin 2 (Internal) is suitable for use in ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Preliminary experiments gave an approx 30-35kDa band in human placenta lysates after 0.3 µg/ml antibody staining. Please note that currently we cannot find an explanation in the litera
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: FBN2
Gene ID: 2201
Uniprot ID: FBN2_HUMAN
Immunogen Region: Internal
Accession Number: NP_001990.2
Immunogen Sequence: KELKKLEESNEDDC
Post Translational Modifications Placensin: N-glycosylated. O-glycosylated on serine residues by POGLUT2 and POGLUT3.
Function Fibrillin-2: Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Placensin: Hormone secreted by trophoblasts that promotes trophoblast invasiveness. Has glucogenic activity: is able to increase plasma glucose levels.
Protein Name Fibrillin-2 Cleaved Into - Placensin
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-1566948
Reactome: R-HSA-2129379
Cellular Localisation Secreted
Fibrillin-2 And Placensin Chains Are Still Linked Together During The Secretion From Cells
But Are Subsequently Separated By Furin
Fibrillin-2: Secreted
Extracellular Space
Extracellular Matrix
Placensin: Secreted
Secreted By Placental Cells
Alternative Antibody Names Anti-Fibrillin-2 Cleaved Into - Placensin antibody
Anti-FBN2 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ71046 Anti-Fibrillin 2-Mouse antibody (Internal) (STJ71046) Goat Polyclonal Mouse Pep-ELISA
STJ72158 Anti-Aconitase 2 antibody (Internal) (STJ72158) Goat Polyclonal Human/Mouse/Rat/Dog/Cow/Pig Pep-ELISA/WB/IF/IHC
STJ70743 Anti-Rhophilin 2 antibody (Internal) (STJ70743) Goat Polyclonal Human/Mouse/Rat/Cow Pep-ELISA/IHC
STJ71257 Anti-Neurofibromin 2 antibody (Internal) (STJ71257) Goat Polyclonal Zebrafish Pep-ELISA/IHC
STJ71394 Anti-Tankyrase 2 antibody (Internal) (STJ71394) Goat Polyclonal Human/Mouse/Dog Pep-ELISA/WB
STJ71475 Anti-Frizzled 2 antibody (Internal) (STJ71475) Goat Polyclonal Human/Mouse/Rat Pep-ELISA/WB/IF/IHC
STJ71291 Anti-Fascin 2 antibody (Internal) (STJ71291) Goat Polyclonal Human/Mouse/Rat/Dog Pep-ELISA/IHC/ICC
STJ92605 Anti-CYP4Z1/2 antibody (Internal) (STJ92605) Rabbit Polyclonal Human/Rat/Mouse WB/IHC/IF/ELISA
STJ72095 Anti-Prokineticin 2 antibody (Internal) (STJ72095) Goat Polyclonal Human Pep-ELISA/IHC
!