| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FGF9 |
| Gene ID: | 2254 |
| Uniprot ID: | FGF9_HUMAN |
| Immunogen Region: | 1-50 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGF9 (NP_002001.1). |
| Immunogen Sequence: | MAPLGEVGNYFGVQDAVPFG NVPVLPVDSPVLLSDHLGQS EAGGLPRGPAVTDLDHLKGI LRRRQLYCRTGFHLEIFPNG TIQGTRKDHSRFGILEFISI |
| Tissue Specificity | Glial cells. |
| Post Translational Modifications | Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step. N-glycosylated. |
| Function | Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. |
| Protein Name | Fibroblast Growth Factor 9Fgf-9Glia-Activating FactorGafHeparin-Binding Growth Factor 9Hbgf-9 |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1257604Reactome: R-HSA-1839122Reactome: R-HSA-1839130Reactome: R-HSA-190322Reactome: R-HSA-190371Reactome: R-HSA-190372Reactome: R-HSA-190373Reactome: R-HSA-190375Reactome: R-HSA-2033519Reactome: R-HSA-2219530Reactome: R-HSA-5654219Reactome: R-HSA-5654221Reactome: R-HSA-5654227Reactome: R-HSA-5654228Reactome: R-HSA-5654687Reactome: R-HSA-5654688Reactome: R-HSA-5654689Reactome: R-HSA-5654693Reactome: R-HSA-5654695Reactome: R-HSA-5654699Reactome: R-HSA-5654700Reactome: R-HSA-5654704Reactome: R-HSA-5654706Reactome: R-HSA-5654710Reactome: R-HSA-5654712Reactome: R-HSA-5654719Reactome: R-HSA-5654720Reactome: R-HSA-5654726Reactome: R-HSA-5654727Reactome: R-HSA-5654732Reactome: R-HSA-5654733Reactome: R-HSA-5655253Reactome: R-HSA-5655302Reactome: R-HSA-5655332Reactome: R-HSA-5673001Reactome: R-HSA-6811558Reactome: R-HSA-9690406 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 9 antibodyAnti-Fgf-9 antibodyAnti-Glia-Activating Factor antibodyAnti-Gaf antibodyAnti-Heparin-Binding Growth Factor 9 antibodyAnti-Hbgf-9 antibodyAnti-FGF9 antibody |
Information sourced from Uniprot.org