| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FECH |
| Gene ID: | 2235 |
| Uniprot ID: | HEMH_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FECH (NP_000131.2). |
| Immunogen Sequence: | MRSLGANMAAALRAAGVLLR DPLASSSWRVCQPWRWKSGA AAAAVTTETAQHAQGAKPQV QPQKRKPKTGILMLNMGGPE TLGDVHDFLLRLFLDRDLMT LPIQNKLAPFIAKRRTPKIQ EQYRRIGGGSPIKIWTSKQG EGMVKLLDELSPNTAPHKYY IGFRYVHPLTEEAIEEMERD GLERAIAFTQYPQYSCSTTG |
| Function | Catalyzes the ferrous insertion into protoporphyrin IX and participates in the terminal step in the heme biosynthetic pathway. |
| Protein Name | Ferrochelatase - MitochondrialHeme SynthaseProtoheme Ferro-Lyase |
| Database Links | Reactome: R-HSA-189451Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Ferrochelatase - Mitochondrial antibodyAnti-Heme Synthase antibodyAnti-Protoheme Ferro-Lyase antibodyAnti-FECH antibody |
Information sourced from Uniprot.org
