| Short Description : | Rabbit monoclonal Adrenodoxin-Mitochondrial antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM13100 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB, 1:1000-1:2000IHC-P, 1:2000-1:8000IF/ICC, 1:100-1:400ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FDX1 |
| Gene ID: | 2230 |
| Uniprot ID: | ADX_HUMAN |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Immunogen Sequence: | Human |
| Function | Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
| Protein Name | Adrenodoxin - MitochondrialAdrenal FerredoxinFerredoxin-1Hepatoredoxin |
| Database Links | Reactome: R-HSA-1362409Reactome: R-HSA-196108Reactome: R-HSA-211976Reactome: R-HSA-2395516Reactome: R-HSA-5579026Reactome: R-HSA-9857492 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Adrenodoxin - Mitochondrial antibodyAnti-Adrenal Ferredoxin antibodyAnti-Ferredoxin-1 antibodyAnti-Hepatoredoxin antibodyAnti-FDX1 antibodyAnti-ADX antibody |
Information sourced from Uniprot.org
