Post Translational Modifications | Phosphorylated on tyrosines upon activation. |
Function | Type I transmembrane surface glycoprotein preferentially expressed by B-cells that regulates BCR-mediated signaling responses. Recruits ABL1 as the intracellular effector molecule to enhance B-cell activation. Plays also a negative role by suppressing ERK activation under homeostatic and BCR-stimulated conditions in a GRB2-dependent manner. |
Protein Name | Fc Receptor-Like Protein 1Fcr-Like Protein 1Fcrl1Fc Receptor Homolog 1Fcrh1Ifgp Family Protein 1Hifgp1Immune Receptor Translocation-Associated Protein 5Cd Antigen Cd307a |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Fc Receptor-Like Protein 1 antibodyAnti-Fcr-Like Protein 1 antibodyAnti-Fcrl1 antibodyAnti-Fc Receptor Homolog 1 antibodyAnti-Fcrh1 antibodyAnti-Ifgp Family Protein 1 antibodyAnti-Hifgp1 antibodyAnti-Immune Receptor Translocation-Associated Protein 5 antibodyAnti-Cd Antigen Cd307a antibodyAnti-FCRL1 antibodyAnti-FCRH1 antibodyAnti-IFGP1 antibodyAnti-IRTA5 antibody |
Information sourced from Uniprot.org