• Immunohistochemistry analysis of CD23 in paraffin-embedded human tonsil tissue using CD23 Rabbit polyclonal antibody (STJ11105562) at a dilution of 1:100 (40x lens). High pressure antigen retrieval was performed with 0. 01 M citrate buffer (pH 6. 0) prior to immunohistochemistry staining.
  • Western blot analysis of lysates from Mouse lung using CD23 Rabbit polyclonal antibody (STJ11105562) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25  Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-FCER2 antibody (48-321) (STJ11105562)

SKU:
STJ11105562

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Low Affinity Immunoglobulin Epsilon Fc Receptor (48-321) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCER2
Gene ID: 2208
Uniprot ID: FCER2_HUMAN
Immunogen Region: 48-321
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 48-321 of human CD23 (NP_001993.2).
Immunogen Sequence: DTTQSLKQLEERAARNVSQV SKNLESHHGDQMAQKSQSTQ ISQELEELRAEQQRLKSQDL ELSWNLNGLQADLSSFKSQE LNERNEASDLLERLREEVTK LRMELQVSSGFVCNTCPEKW INFQRKCYYFGKGTKQWVHA RYACDDMEGQLVSIHSPEEQ DFLTKHASHTGSWIGLRNLD LKGEFIWVDGSHVDYSNWAP GEPTSRSQGEDCVMMRGSGR WNDAFCDRKLGAWVCDRLA
Post Translational Modifications N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
Protein Name Low Affinity Immunoglobulin Epsilon Fc Receptor
Blast-2
C-Type Lectin Domain Family 4 Member J
Fc-Epsilon-Rii
Immunoglobulin E-Binding Factor
Lymphocyte Ige Receptor
Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form
Database Links Reactome: R-HSA-2197563
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Lipid-Anchor
Secreted
Also Exists As A Soluble Excreted Form
Scd23
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody
Anti-Blast-2 antibody
Anti-C-Type Lectin Domain Family 4 Member J antibody
Anti-Fc-Epsilon-Rii antibody
Anti-Immunoglobulin E-Binding Factor antibody
Anti-Lymphocyte Ige Receptor antibody
Anti-Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibody
Anti-FCER2 antibody
Anti-CD23A antibody
Anti-CLEC4J antibody
Anti-FCE2 antibody
Anti-IGEBF antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance