Anti-FBLN1 antibody (266-402 aa) [R09-9C1] (STJA0011318)

SKU:
STJA0011318-100

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Host: Rabbit
Applications: WB/IP
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Fibulin 1 (266-402 aa) is suitable for use in Western Blot and Immunoprecipitation research applications.
Clonality: Monoclonal
Clone ID: R09-9C1
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/ml
Dilution Range: WB 1:500-1:1000
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: FBLN1
Gene ID: 2192
Uniprot ID: FBLN1_HUMAN
Immunogen Region: 266-402 aa
Immunogen: Recombinant protein of human Fibulin 1
Tissue Specificity Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells.
Function Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.
Protein Name Fibulin-1
Fibl-1
Database Links Reactome: R-HSA-2129379
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-Fibulin-1 antibody
Anti-Fibl-1 antibody
Anti-FBLN1 antibody
Anti-PP213 antibody

Information sourced from Uniprot.org

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