Anti-FASTKD2 antibody (439-710 aa) (STJ11106211)

SKU:
STJ11106211
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Gene Symbol: FASTKD2
Gene ID: 22868
Uniprot ID: FAKD2_HUMAN
Immunogen Region: 439-710 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 439-710 of human FASTKD2 (NP_055744.2).
Immunogen Sequence: LFMKRIVEDPESLNMKNILS ILHTYSSLNHVYKCQNKEQF VEVMASALTGYLHTISSENL LDAVYSFCLMNYFPLAPFNQ LLQKDIISELLTSDDMKNAY KLHTLDTCLKLDDTVYLRDI ALSLPQLPRELPSSHTNAKV AEVLSSLLGGEGHFSKDVHL PHNYHIDFEIRMDTNRNQVL PLSDVDTTSATDIQRVAVLC VSRSAYCLGSSHPRGFLAMK MRHLNAMGFHVILVNNWEM
Tissue Specificity Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid.
Function Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. May play a role in mitochondrial apoptosis.
Protein Name Fast Kinase Domain-Containing Protein 2 - Mitochondrial
Database Links Reactome: R-HSA-9837092
Cellular Localisation Mitochondrion Matrix
Mitochondrion Nucleoid
Localizes To Mitochondrial Rna Granules Found In Close Proximity To The Mitochondrial Nucleoids
Alternative Antibody Names Anti-Fast Kinase Domain-Containing Protein 2 - Mitochondrial antibody
Anti-FASTKD2 antibody
Anti-KIAA0971 antibody

Information sourced from Uniprot.org