| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FANCA (1-275) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FANCA |
| Gene ID: |
2175 |
| Uniprot ID: |
FANCA_HUMAN |
| Immunogen Region: |
1-275 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human FANCA (NP_000126.2). |
| Immunogen Sequence: |
MSDSWVPNSASGQDPGGRRR AWAELLAGRVKREKYNPERA QKLKESAVRLLRSHQDLNAL LLEVEGPLCKKLSLSKVIDC DSSEAYANHSSSFIGSALQD QASRLGVPVGILSAGMVASS VGQICTAPAETSHPVLLTVE QRKKLSSLLEFAQYLLAHSM FSRLSFCQELWKIQSSLLLE AVWHLHVQGIVSLQELLESH PDMHAVGSWLFRNLCCLCEQ MEASCQHADVARAMLSDFV |
| Post Translational Modifications | Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H. |
| Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. |
| Protein Name | Fanconi Anemia Group A ProteinProtein Faca |
| Database Links | Reactome: R-HSA-6783310 |
| Cellular Localisation | NucleusCytoplasmThe Major Form Is NuclearThe Minor Form Is Cytoplasmic |
| Alternative Antibody Names | Anti-Fanconi Anemia Group A Protein antibodyAnti-Protein Faca antibodyAnti-FANCA antibodyAnti-FAA antibodyAnti-FACA antibodyAnti-FANCH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
