Anti-FANCA antibody (1-275) (STJ29984)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FANCA (1-275) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FANCA |
| Gene ID | 2175 |
| Uniprot ID | FANCA_HUMAN |
| Immunogen Region | 1-275 |
| Immunogen Sequence | MSDSWVPNSASGQDPGGRRR AWAELLAGRVKREKYNPERA QKLKESAVRLLRSHQDLNAL LLEVEGPLCKKLSLSKVIDC DSSEAYANHSSSFIGSALQD QASRLGVPVGILSAGMVASS VGQICTAPAETSHPVLLTVE QRKKLSSLLEFAQYLLAHSM FSRLSFCQELWKIQSSLLLE AVWHLHVQGIVSLQELLESH PDMHAVGSWLFRNLCCLCEQ MEASCQHADVARAMLSDFV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human FANCA (NP_000126.2). |
Additional Info
| Post Translational Modifications | Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H. |
| Function | DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. |
| Protein Name | Fanconi Anemia Group A ProteinProtein Faca |
| Database Links | Reactome: R-HSA-6783310Reactome: R-HSA-9833482 |
| Cellular Localisation | NucleusCytoplasmThe Major Form Is NuclearThe Minor Form Is Cytoplasmic |
| Alternative Antibody Names | Anti-Fanconi Anemia Group A Protein antibodyAnti-Protein Faca antibodyAnti-FANCA antibodyAnti-FAA antibodyAnti-FACA antibodyAnti-FANCH antibody |
Information sourced from Uniprot.org