• Western blot analysis of extracts of HeLa cells, using FANCA antibody (STJ29984) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-FANCA antibody (1-275) (STJ29984)

SKU:
STJ29984

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FANCA (1-275) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FANCA
Gene ID: 2175
Uniprot ID: FANCA_HUMAN
Immunogen Region: 1-275
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human FANCA (NP_000126.2).
Immunogen Sequence: MSDSWVPNSASGQDPGGRRR AWAELLAGRVKREKYNPERA QKLKESAVRLLRSHQDLNAL LLEVEGPLCKKLSLSKVIDC DSSEAYANHSSSFIGSALQD QASRLGVPVGILSAGMVASS VGQICTAPAETSHPVLLTVE QRKKLSSLLEFAQYLLAHSM FSRLSFCQELWKIQSSLLLE AVWHLHVQGIVSLQELLESH PDMHAVGSWLFRNLCCLCEQ MEASCQHADVARAMLSDFV
Post Translational Modifications Phosphorylation is required for the formation of the nuclear complex. Not phosphorylated in cells derived from groups A, B, C, E, F, G, and H.
Function DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
Protein Name Fanconi Anemia Group A Protein
Protein Faca
Database Links Reactome: R-HSA-6783310
Cellular Localisation Nucleus
Cytoplasm
The Major Form Is Nuclear
The Minor Form Is Cytoplasmic
Alternative Antibody Names Anti-Fanconi Anemia Group A Protein antibody
Anti-Protein Faca antibody
Anti-FANCA antibody
Anti-FAA antibody
Anti-FACA antibody
Anti-FANCH antibody

Information sourced from Uniprot.org

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