| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAAH2 |
| Gene ID: | 158584 |
| Uniprot ID: | FAAH2_HUMAN |
| Immunogen Region: | 323-532 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 323-532 of human FAAH2 (NP_777572.2). |
| Immunogen Sequence: | DQDLIMTQKKVVVHLETILG ASVQHVKLKKMKYSFQLWIA MMSAKGHDGKEPVKFVDLLG DHGKHVSPLWELIKWCLGLS VYTIPSIGLALLEEKLRYSN EKYQKFKAVEESLRKELVDM LGDDGVFLYPSHPTVAPKHH VPLTRPFNFAYTGVFSALGL PVTQCPLGLNAKGLPLGIQV VAGPFNDHLTLAVAQYLEKT FGGWVCPGKF |
| Tissue Specificity | Expressed in kidney, liver, lung, prostate, heart and ovary. |
| Function | Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. |
| Protein Name | Fatty-Acid Amide Hydrolase 2Amidase Domain-Containing ProteinAnandamide Amidohydrolase 2Oleamide Hydrolase 2 |
| Database Links | Reactome: R-HSA-2142753 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinLipid Droplet |
| Alternative Antibody Names | Anti-Fatty-Acid Amide Hydrolase 2 antibodyAnti-Amidase Domain-Containing Protein antibodyAnti-Anandamide Amidohydrolase 2 antibodyAnti-Oleamide Hydrolase 2 antibodyAnti-FAAH2 antibodyAnti-AMDD antibody |
Information sourced from Uniprot.org