| Host: | Rabbit |
| Applications: | IHC-P/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S5223RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Adgre1 |
| Gene ID: | 13733 |
| Uniprot ID: | AGRE1_MOUSE |
| Immunogen Region: | 367-645 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 367-645 of mouse F4/80 (NP_034260.1). |
| Immunogen Sequence: | KRILFKCKEDLILQSEQIQQ CQAVQGRDLGYASFCTLVNA TFTILDNTCENKSAPVSLQS AATSVSLVLEQATTWFELSK EETSTLGTILLETVESTMLA ALLIPSGNASQMIQTEYLDI ESKVINEECKENESINLAAR GDKMNVGCFIIKESVSTGAP GVAFVSFAHMESVLNERFFE DGQSFRKLRMNSRVVGGTVT GEKKEDFSKPIIYTLQHIQP KQKSERPICVSWNTDVEDG |
| Tissue Specificity | In macrophages.but absent from those which are localized within T-cell areas of lymph nodes and spleen. Low level of expression on blood monocytes. |
| Function | Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. |
| Protein Name | Adhesion G Protein-Coupled Receptor E1Cell Surface Glycoprotein F4/80Egf-Like Module Receptor 1Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1Emr1 Hormone Receptor |
| Database Links | Reactome: R-MMU-373080 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E1 antibodyAnti-Cell Surface Glycoprotein F4/80 antibodyAnti-Egf-Like Module Receptor 1 antibodyAnti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 antibodyAnti-Emr1 Hormone Receptor antibodyAnti-Adgre1 antibodyAnti-Emr1 antibodyAnti-Gpf480 antibody |
Information sourced from Uniprot.org