| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | F3 |
| Gene ID: | 2152 |
| Uniprot ID: | TF_HUMAN |
| Immunogen Region: | 120-251 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-251 of human Coagulation factor III/Tissue Factor (NP_001984.1). |
| Immunogen Sequence: | SAGEPLYENSPEFTPYLETN LGQPTIQSFEQVGTKVNVTV EDERTLVRRNNTFLSLRDVF GKDLIYTLYYWKSSSSGKKT AKTNTNEFLIDVDKGENYCF SVQAVIPSRTVNRKSTDSPV ECMGQEKGEFRE |
| Tissue Specificity | Lung, placenta and pancreas. |
| Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The TF:VIIa complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
| Protein Name | Tissue FactorTfCoagulation Factor IiiThromboplastinCd Antigen Cd142 |
| Database Links | Reactome: R-HSA-140834Reactome: R-HSA-9031628 |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Tissue Factor antibodyAnti-Tf antibodyAnti-Coagulation Factor Iii antibodyAnti-Thromboplastin antibodyAnti-Cd Antigen Cd142 antibodyAnti-F3 antibody |
Information sourced from Uniprot.org