Host: |
Mouse |
Applications: |
IHC/IF/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Coagulation factor XIII A chain (400-500 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
ABT170 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1k |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Dilution Range: |
IHC-P 1:100-500WB 1:200-1000IF 1:100-500 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
F13A1 |
Gene ID: |
2162 |
Uniprot ID: |
F13A_HUMAN |
Immunogen Region: |
400-500 aa |
Specificity: |
The antibody can specifically recognize human Factor XIIIa protein. In western blotting of A431 cell lysates, there shows a 100KDa band detected by the antibody. |
Immunogen: |
Synthesized peptide derived from the human Factor XIIIa at the amino acid range 400-500 |
Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
Protein Name | Coagulation Factor Xiii A ChainCoagulation Factor XiiiaProtein-Glutamine Gamma-Glutamyltransferase A ChainTransglutaminase A Chain |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140875Reactome: R-HSA-6785807 |
Cellular Localisation | CytoplasmSecretedSecreted Into The Blood PlasmaCytoplasmic In Most TissuesBut Also Secreted In The Blood Plasma |
Alternative Antibody Names | Anti-Coagulation Factor Xiii A Chain antibodyAnti-Coagulation Factor Xiiia antibodyAnti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibodyAnti-Transglutaminase A Chain antibodyAnti-F13A1 antibodyAnti-F13A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance