| Short Description : | Mouse monoclonal anti-Coagulation factor XIII A chain (400-500 aa) for use in IHC, IF and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/IF/WB |
| Host: | Mouse |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ABT170 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | IHC-P 1:100-500WB 1:200-1000IF 1:100-500 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | F13A1 |
| Gene ID: | 2162 |
| Uniprot ID: | F13A_HUMAN |
| Immunogen: | Synthesized peptide derived from the human Factor XIIIa at the amino acid range 400-500 |
| Immunogen Region: | 400-500 aa |
| Specificity: | The antibody can specifically recognize human Factor XIIIa protein. In western blotting of A431 cell lysates, there shows a 100KDa band detected by the antibody. |
| Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
| Protein Name | Coagulation Factor Xiii A ChainCoagulation Factor XiiiaProtein-Glutamine Gamma-Glutamyltransferase A ChainTransglutaminase A Chain |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140875Reactome: R-HSA-6785807 |
| Cellular Localisation | CytoplasmSecretedSecreted Into The Blood PlasmaCytoplasmic In Most TissuesBut Also Secreted In The Blood Plasma |
| Alternative Antibody Names | Anti-Coagulation Factor Xiii A Chain antibodyAnti-Coagulation Factor Xiiia antibodyAnti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibodyAnti-Transglutaminase A Chain antibodyAnti-F13A1 antibodyAnti-F13A antibody |
Information sourced from Uniprot.org
