| Host: | Rabbit |
| Applications: | WB/IF/ICC/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EXOC2 |
| Gene ID: | 55770 |
| Uniprot ID: | EXOC2_HUMAN |
| Immunogen Region: | 1-220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human EXOC2 (NP_060773.3). |
| Immunogen Sequence: | MSRSRQPPLVTGISPNEGIP WTKVTIRGENLGTGPTDLIG LTICGHNCLLTAEWMSASKI VCRVGQAKNDKGDIIVTTKS GGRGTSTVSFKLLKPEKIGI LDQSAVWVDEMNYYDMRTDR NKGIPPLSLRPANPLGIEIE KSKFSQKDLEMLFHGMSADF TSENFSAAWYLIENHSNTSF EQLKMAVTNLKRQANKKSEG SLAYVKGGLSTFFEAQDALS |
| Tissue Specificity | Widely expressed with highest levels in brain and placenta. |
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. |
| Protein Name | Exocyst Complex Component 2Exocyst Complex Component Sec5 |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-264876Reactome: R-HSA-5620916 |
| Cellular Localisation | MidbodyMidbody RingRecruitment To The Midbody Does Not Require RalaNor RalbColocalizes With Cntrl/Centriolin At The Midbody Ring |
| Alternative Antibody Names | Anti-Exocyst Complex Component 2 antibodyAnti-Exocyst Complex Component Sec5 antibodyAnti-EXOC2 antibodyAnti-SEC5 antibodyAnti-SEC5L1 antibody |
Information sourced from Uniprot.org