| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transcription factor ETV6 (223-272 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ETV6 |
| Gene ID: |
2120 |
| Uniprot ID: |
ETV6_HUMAN |
| Immunogen Region: |
223-272 aa |
| Specificity: |
TEL Polyclonal Antibody detects endogenous levels of TEL protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human Tel at the amino acid range 223-272 |
| Post Translational Modifications | Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression. |
| Function | Transcriptional repressor.binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation. |
| Protein Name | Transcription Factor Etv6Ets Translocation Variant 6Ets-Related Protein Tel1Tel |
| Database Links | Reactome: R-HSA-9673768Reactome: R-HSA-9703465 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Etv6 antibodyAnti-Ets Translocation Variant 6 antibodyAnti-Ets-Related Protein Tel1 antibodyAnti-Tel antibodyAnti-ETV6 antibodyAnti-TEL antibodyAnti-TEL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
