Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Mouse/Dog |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-ESRRG (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
ELISA-antibody detection limit dilution 1:16000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
ESRRG |
Gene ID: |
2104 |
Uniprot ID: |
ERR3_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_001429.2; NP_996317.1; NP_996318.1 |
Specificity: |
This antibody is expected to recognise the reported isoform NP_001429.2. |
Immunogen Sequence: |
CRMSNKDRHIDS |
Post Translational Modifications | Acetylated by PCAF/KAT2 (in vitro). Sumoylation on Lys-40 is enhanced by phosphorylation at Ser-45 and represses transcriptional activity. Phosphorylation on Ser-45 enhances sumoylation on Lys-40 thus repressing transcriptional activity. |
Function | Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Induces the expression of PERM1 in the skeletal muscle. |
Protein Name | Estrogen-Related Receptor GammaErr Gamma-2Estrogen Receptor-Related Protein 3Nuclear Receptor Subfamily 3 Group B Member 3 |
Database Links | Reactome: R-HSA-383280 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Estrogen-Related Receptor Gamma antibodyAnti-Err Gamma-2 antibodyAnti-Estrogen Receptor-Related Protein 3 antibodyAnti-Nuclear Receptor Subfamily 3 Group B Member 3 antibodyAnti-ESRRG antibodyAnti-ERR3 antibodyAnti-ERRG2 antibodyAnti-KIAA0832 antibodyAnti-NR3B3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance