• Various whole cell lysates were separated by 8% SDS-PAGE, and the membrane was blotted with anti-ER-β (PT0318) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: Hela Lane 2: HEK293 Lane 3: MCF7Predicted band size: 59kDaObserved band size: 59kDa

Anti-ESR2 antibody (400-530 aa) (STJ196169)

SKU:
STJ196169

£46.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/IF/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Estrogen receptor beta (400-530 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and Western Blot research applications.
Clonality: Monoclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-300
WB 1:500-2000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ESR2
Gene ID: 2100
Uniprot ID: ESR2_HUMAN
Immunogen Region: 400-530 aa
Specificity: This antibody detects endogenous levels of human Estrogen Receptor Beta
Immunogen: Synthesized peptide derived from the human Estrogen Receptor Beta at the amino acid range 400-530
Post Translational Modifications Phosphorylation at Ser-87 and Ser-105 recruits NCOA1.
Function Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform 2: Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability.
Protein Name Estrogen Receptor Beta
Er-Beta
Nuclear Receptor Subfamily 3 Group A Member 2
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-383280
Reactome: R-HSA-6811558
Reactome: R-HSA-8939211
Reactome: R-HSA-9009391
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Estrogen Receptor Beta antibody
Anti-Er-Beta antibody
Anti-Nuclear Receptor Subfamily 3 Group A Member 2 antibody
Anti-ESR2 antibody
Anti-ESTRB antibody
Anti-NR3A2 antibody

Information sourced from Uniprot.org

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