| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ERP44 |
| Gene ID: | 23071 |
| Uniprot ID: | ERP44_HUMAN |
| Immunogen Region: | 57-406 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 57-406 of human ERP44 (NP_055866.1). |
| Immunogen Sequence: | WCRFSQMLHPIFEEASDVIK EEFPNENQVVFARVDCDQHS DIAQRYRISKYPTLKLFRNG MMMKREYRGQRSVKALADYI RQQKSDPIQEIRDLAEITTL DRSKRNIIGYFEQKDSDNYR VFERVANILHDDCAFLSAFG DVSKPERYSGDNIIYKPPGH SAPDMVYLGAMTNFDVTYNW IQDKCVPLVREITFENGEEL TEEGLPFLILFHMKEDTESL EIFQNEVARQLISEKGTIN |
| Function | Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum. |
| Protein Name | Endoplasmic Reticulum Resident Protein 44Er Protein 44Erp44Thioredoxin Domain-Containing Protein 4 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Endoplasmic Reticulum Resident Protein 44 antibodyAnti-Er Protein 44 antibodyAnti-Erp44 antibodyAnti-Thioredoxin Domain-Containing Protein 4 antibodyAnti-ERP44 antibodyAnti-KIAA0573 antibodyAnti-TXNDC4 antibodyAnti-UNQ532 antibodyAnti-PRO1075 antibody |
Information sourced from Uniprot.org