Anti-ERCC6L2 antibody (STJA0008974)

SKU:
STJA0008974
€61.25 - €326.25
Processing The item has been added

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal anti-DNA excision repair protein ERCC-6-like 2 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERCC6L2
Gene ID: 375748
Uniprot ID: ER6L2_HUMAN
Specificity: This antibody detects endogenous levels of ERCC6L2 at Human, Mouse
Immunogen: Synthesized peptide derived from human ERCC6L2
Post Translational Modifications Phosphorylated by NEK6.
Function Promotes double-strand break (DSB) end-joining and facilitates programmed recombination by controlling how DNA ends are joined in a spatially oriented manner during repair. Also plays a role in DNA repair by restricting DNA end resection in double strand break (DSB) repair. Facilitates replication of complex DNA regions and regulates the maintenance of chromatin structure.
Protein Name Dna Excision Repair Protein Ercc-6-Like 2
Dna Repair And Recombination Protein Rad26-Like
Excision Repair Cross-Complementation Group 6-Like 2
Database Links
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Mitochondrion
Chromosome
Centromere
Colocalizes With Nek6 In The Centrosome
In Response To Dna Damage
Translocates From The Cytosol To Mitochondria And Nucleus In A Reactive Oxygen Species (Ros)-Dependent Manner
Centromeric Localization Is Facilitated By Its Interaction With Pcna
Alternative Antibody Names Anti-Dna Excision Repair Protein Ercc-6-Like 2 antibody
Anti-Dna Repair And Recombination Protein Rad26-Like antibody
Anti-Excision Repair Cross-Complementation Group 6-Like 2 antibody
Anti-ERCC6L2 antibody
Anti-C9orf102 antibody
Anti-RAD26L antibody

Information sourced from Uniprot.org