| Post Translational Modifications | Phosphorylated by NEK6. |
| Function | Promotes double-strand break (DSB) end-joining and facilitates programmed recombination by controlling how DNA ends are joined in a spatially oriented manner during repair. Also plays a role in DNA repair by restricting DNA end resection in double strand break (DSB) repair. Facilitates replication of complex DNA regions and regulates the maintenance of chromatin structure. |
| Protein Name | Dna Excision Repair Protein Ercc-6-Like 2Dna Repair And Recombination Protein Rad26-LikeExcision Repair Cross-Complementation Group 6-Like 2 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMitochondrionChromosomeCentromereColocalizes With Nek6 In The CentrosomeIn Response To Dna DamageTranslocates From The Cytosol To Mitochondria And Nucleus In A Reactive Oxygen Species (Ros)-Dependent MannerCentromeric Localization Is Facilitated By Its Interaction With Pcna |
| Alternative Antibody Names | Anti-Dna Excision Repair Protein Ercc-6-Like 2 antibodyAnti-Dna Repair And Recombination Protein Rad26-Like antibodyAnti-Excision Repair Cross-Complementation Group 6-Like 2 antibodyAnti-ERCC6L2 antibodyAnti-C9orf102 antibodyAnti-RAD26L antibody |
Information sourced from Uniprot.org