Anti-ENPEP antibody (708-957) (STJ28985)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ENPEP (708-957) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ENPEP |
| Gene ID | 2028 |
| Uniprot ID | AMPE_HUMAN |
| Immunogen Region | 708-957 |
| Immunogen Sequence | DDKELYPMIEEYFQGQVKPI ADSLGWNDAGDHVTKLLRSS VLGFACKMGDREALNNASSL FEQWLNGTVSLPVNLRLLVY RYGMQNSGNEISWNYTLEQY QKTSLAQEKEKLLYGLASVK NVTLLSRYLDLLKDTNLIKT QDVFTVIRYISYNSYGKNMA WNWIQLNWDYLVNRYTLNNR NLGRIVTIAEPFNTELQLWQ MESFFAKYPQAGAGEKPREQ VLETVKNNIEWLKQHRNTI |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 708-957 of human ENPEP (NP_001968.3). |
Additional Info
| Tissue Specificity | Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
| Function | Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. |
| Protein Name | Glutamyl AminopeptidaseEapAminopeptidase AAp-ADifferentiation Antigen Gp160Cd Antigen Cd249 |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Glutamyl Aminopeptidase antibodyAnti-Eap antibodyAnti-Aminopeptidase A antibodyAnti-Ap-A antibodyAnti-Differentiation Antigen Gp160 antibodyAnti-Cd Antigen Cd249 antibodyAnti-ENPEP antibody |
Information sourced from Uniprot.org