Host: |
Rabbit |
Applications: |
WB/IHC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ENPEP (708-957) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ENPEP |
Gene ID: |
2028 |
Uniprot ID: |
AMPE_HUMAN |
Immunogen Region: |
708-957 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 708-957 of human ENPEP (NP_001968.3). |
Immunogen Sequence: |
DDKELYPMIEEYFQGQVKPI ADSLGWNDAGDHVTKLLRSS VLGFACKMGDREALNNASSL FEQWLNGTVSLPVNLRLLVY RYGMQNSGNEISWNYTLEQY QKTSLAQEKEKLLYGLASVK NVTLLSRYLDLLKDTNLIKT QDVFTVIRYISYNSYGKNMA WNWIQLNWDYLVNRYTLNNR NLGRIVTIAEPFNTELQLWQ MESFFAKYPQAGAGEKPREQ VLETVKNNIEWLKQHRNTI |
Tissue Specificity | Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
Function | Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. |
Protein Name | Glutamyl AminopeptidaseEapAminopeptidase AAp-ADifferentiation Antigen Gp160Cd Antigen Cd249 |
Database Links | Reactome: R-HSA-2022377 |
Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Glutamyl Aminopeptidase antibodyAnti-Eap antibodyAnti-Aminopeptidase A antibodyAnti-Ap-A antibodyAnti-Differentiation Antigen Gp160 antibodyAnti-Cd Antigen Cd249 antibodyAnti-ENPEP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance