| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ENPEP |
| Gene ID: | 2028 |
| Uniprot ID: | AMPE_HUMAN |
| Immunogen Region: | 708-957 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 708-957 of human ENPEP (NP_001968.3). |
| Immunogen Sequence: | DDKELYPMIEEYFQGQVKPI ADSLGWNDAGDHVTKLLRSS VLGFACKMGDREALNNASSL FEQWLNGTVSLPVNLRLLVY RYGMQNSGNEISWNYTLEQY QKTSLAQEKEKLLYGLASVK NVTLLSRYLDLLKDTNLIKT QDVFTVIRYISYNSYGKNMA WNWIQLNWDYLVNRYTLNNR NLGRIVTIAEPFNTELQLWQ MESFFAKYPQAGAGEKPREQ VLETVKNNIEWLKQHRNTI |
| Tissue Specificity | Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
| Function | Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. |
| Protein Name | Glutamyl Aminopeptidase Eap Aminopeptidase A Ap-A Differentiation Antigen Gp160 Cd Antigen Cd249 |
| Database Links | Reactome: R-HSA-2022377 |
| Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Glutamyl Aminopeptidase antibody Anti-Eap antibody Anti-Aminopeptidase A antibody Anti-Ap-A antibody Anti-Differentiation Antigen Gp160 antibody Anti-Cd Antigen Cd249 antibody Anti-ENPEP antibody |
Information sourced from Uniprot.org