| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Uridylate-specific endoribonuclease (32-82 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ENDOU |
| Gene ID: | 8909 |
| Uniprot ID: | ENDOU_HUMAN |
| Immunogen Region: | 32-82 aa |
| Specificity: | This antibody detects endogenous levels of human ENDOU |
| Immunogen: | Synthesized peptide derived from the human ENDOU at the amino acid range 32-82 |
| Post Translational Modifications | It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. |
| Function | Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites. Targets mRNAs to regulate their expression. |
| Protein Name | Uridylate-Specific EndoribonucleasePlacental Protein 11Pp11Protein Endou |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Uridylate-Specific Endoribonuclease antibodyAnti-Placental Protein 11 antibodyAnti-Pp11 antibodyAnti-Protein Endou antibodyAnti-ENDOU antibody |
Information sourced from Uniprot.org