| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-ENC1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
ENC1 |
| Gene ID: |
8507 |
| Uniprot ID: |
ENC1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_003624.1; NP_001243505.1 |
| Specificity: |
This antibody is expected to recognize both reported isoforms (NP_003624.1; NP_001243505.1). Reported variants represent identical protein: NP_001243503.1, NP_001243504.1, NP_003624.1. |
| Immunogen Sequence: |
TSVSHDKLPKVQC |
| Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination. |
| Function | Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism. |
| Protein Name | Ectoderm-Neural Cortex Protein 1Enc-1Kelch-Like Protein 37Nuclear Matrix Protein Nrp/BP53-Induced Gene 10 Protein |
| Cellular Localisation | Nucleus MatrixCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Ectoderm-Neural Cortex Protein 1 antibodyAnti-Enc-1 antibodyAnti-Kelch-Like Protein 37 antibodyAnti-Nuclear Matrix Protein Nrp/B antibodyAnti-P53-Induced Gene 10 Protein antibodyAnti-ENC1 antibodyAnti-KLHL37 antibodyAnti-NRPB antibodyAnti-PIG10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
