Anti-ELOVL2 antibody (250-296 aa) (STJ92901)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ELOVL2 at the amino acid range 250-296
General Information
| Short Description | Rabbit polyclonal anti-Elongation of very long chain fatty acids protein 2 (250-296 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ELOVL2 |
| Gene ID | 54898 |
| Uniprot ID | ELOV2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ELOVL2 at the amino acid range 250-296 |
| Immunogen Region | 250-296 aa |
| Specificity | ELOVL2 Polyclonal Antibody detects endogenous levels of ELOVL2 protein. |
Additional Info
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Very Long Chain Fatty Acid Elongase 23-Keto Acyl-Coa Synthase Elovl2Elovl Fatty Acid Elongase 2Elovl Fa Elongase 2Elongation Of Very Long Chain Fatty Acids Protein 2Very Long Chain 3-Ketoacyl-Coa Synthase 2Very Long Chain 3-Oxoacyl-Coa Synthase 2 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 2 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl2 antibodyAnti-Elovl Fatty Acid Elongase 2 antibodyAnti-Elovl Fa Elongase 2 antibodyAnti-Elongation Of Very Long Chain Fatty Acids Protein 2 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 2 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 2 antibodyAnti-ELOVL2 antibodyAnti-ELG3 antibodyAnti-SSC2 antibody |
Information sourced from Uniprot.org