| Tissue Specificity | Liver and testis. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Very Long Chain Fatty Acid Elongase 23-Keto Acyl-Coa Synthase Elovl2Elovl Fatty Acid Elongase 2Elovl Fa Elongase 2Elongation Of Very Long Chain Fatty Acids Protein 2Very Long Chain 3-Ketoacyl-Coa Synthase 2Very Long Chain 3-Oxoacyl-Coa Synthase 2 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Very Long Chain Fatty Acid Elongase 2 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl2 antibodyAnti-Elovl Fatty Acid Elongase 2 antibodyAnti-Elovl Fa Elongase 2 antibodyAnti-Elongation Of Very Long Chain Fatty Acids Protein 2 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 2 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 2 antibodyAnti-ELOVL2 antibodyAnti-ELG3 antibodyAnti-SSC2 antibody |
Information sourced from Uniprot.org
