| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ELOVL2 (247-296) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ELOVL2 |
| Gene ID: |
54898 |
| Uniprot ID: |
ELOV2_HUMAN |
| Immunogen Region: |
247-296 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 247-296 of human ELOVL2 (NP_060240.3). |
| Immunogen Sequence: |
ILFLNFYVQTYRKKPMKKDM QEPPAGKEVKNGFSKAYFTA ANGVMNKKAQ |
| Tissue Specificity | Liver and testis. |
| Function | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
| Protein Name | Elongation Of Very Long Chain Fatty Acids Protein 23-Keto Acyl-Coa Synthase Elovl2Elovl Fatty Acid Elongase 2Elovl Fa Elongase 2Very Long Chain 3-Ketoacyl-Coa Synthase 2Very Long Chain 3-Oxoacyl-Coa Synthase 2 |
| Database Links | Reactome: R-HSA-2046105Reactome: R-HSA-2046106Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Elongation Of Very Long Chain Fatty Acids Protein 2 antibodyAnti-3-Keto Acyl-Coa Synthase Elovl2 antibodyAnti-Elovl Fatty Acid Elongase 2 antibodyAnti-Elovl Fa Elongase 2 antibodyAnti-Very Long Chain 3-Ketoacyl-Coa Synthase 2 antibodyAnti-Very Long Chain 3-Oxoacyl-Coa Synthase 2 antibodyAnti-ELOVL2 antibodyAnti-ELG3 antibodyAnti-SSC2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
