Anti-EIF2A antibody (450-550) [S0MR] (STJ11102530)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal eIF2A (450-550) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S0MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EIF2A |
| Gene ID | 83939 |
| Uniprot ID | EIF2A_HUMAN |
| Immunogen Region | 450-550 |
| Immunogen Sequence | ALRNKPITNSKLHEEEPPQN MKPQSGNDKPLSKTALKNQR KHEAKKAAKQEARSDKSPDL APTPAPQSTPRNTVSQSISG DPEIDKKIKNLKKKLKAIEQ L |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 450-550 of human eIF2A (Q9BY44). |
Additional Info
| Tissue Specificity | Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta. |
| Function | Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. |
| Protein Name | Eukaryotic Translation Initiation Factor 2aEif-2a65 Kda Eukaryotic Translation Initiation Factor 2a Cleaved Into - Eukaryotic Translation Initiation Factor 2a - N-Terminally Processed |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Eukaryotic Translation Initiation Factor 2a antibodyAnti-Eif-2a antibodyAnti-65 Kda Eukaryotic Translation Initiation Factor 2a Cleaved Into - Eukaryotic Translation Initiation Factor 2a - N-Terminally Processed antibodyAnti-EIF2A antibodyAnti-CDA02 antibodyAnti-MSTP004 antibodyAnti-MSTP089 antibody |
Information sourced from Uniprot.org