Function | Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. |
Protein Name | PikachurinAgrin-Like ProteinEgf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein |
Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixSynaptic CleftPresynaptic Active ZoneDetected In The Synaptic Cleft Of The Ribbon Synapse Around The Postsynaptic Terminals Of Bipolar CellsColocalizes With BsnCtbp2 And Dag1 In Photoreceptor Synaptic Terminals |
Alternative Antibody Names | Anti-Pikachurin antibodyAnti-Agrin-Like Protein antibodyAnti-Egf-Like - Fibronectin Type-Iii And Laminin G-Like Domain-Containing Protein antibodyAnti-EGFLAM antibodyAnti-AGRINL antibodyAnti-AGRNL antibodyAnti-PIKA antibody |
Information sourced from Uniprot.org