Anti-EDG8/SPPR1 antibody (Internal) (STJ71984)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-EDG8/SPPR1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx 38kDa band observed in Human Brain (Frontal Cortex and Amygdala) lysates (calculated MW of 41.8kDa according to NP_110387.1). Recommended concentration: 1-3ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | S1PR5 |
| Gene ID | 53637 |
| Uniprot ID | S1PR5_HUMAN |
| Accession Number | NP_110387.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | SGSERSSPQRDGLD |
Additional Info
| Function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. |
| Protein Name | Sphingosine 1-Phosphate Receptor 5S1p Receptor 5S1p5Endothelial Differentiation G-Protein-Coupled Receptor 8Sphingosine 1-Phosphate Receptor Edg-8S1p Receptor Edg-8 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-419408 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Sphingosine 1-Phosphate Receptor 5 antibodyAnti-S1p Receptor 5 antibodyAnti-S1p5 antibodyAnti-Endothelial Differentiation G-Protein-Coupled Receptor 8 antibodyAnti-Sphingosine 1-Phosphate Receptor Edg-8 antibodyAnti-S1p Receptor Edg-8 antibodyAnti-S1PR5 antibodyAnti-EDG8 antibody |
Information sourced from Uniprot.org